Mister Sinister Marvel Comics T-ShirtMister Sinister was born Nathaniel Essex, a scientist who was obsessed with engineering humanity into a perfect race of superhumans. Apocalypse used alien Celestial technology to transform the Essex into Mister Sinister, an ageless man with super powers. Mister Sinister increases his power through self experimentation, and he has developed a great interest in the mutant heroes Cyclops and Jean Grey, believing their DNA can create the ultimate mutant.