Zakrzewska, Marie Elisabeth. (1829 – 1902) Autograph SignatureAutograph signature and salutation dated March 28, [18]74 of the Polish American physician who made her name as a pioneering female doctor in the United States. Mounted to a larger sheet, overall 6. 5 x 2. 5 inches; 16. 5 x 6. 5 cm. Fine. As a Berlin native, she found great interest in medicine after assisting her mother, who worked as a midwife. Best known for the establishment of the New England Hospital for Women and Children, she opened doors to